cialisblack.org
any information about Black Cialis

Cialis Black Active Ingredient: The Principle of Tadalafil Action

Each drug contains both active and inactive ingredients which either provide a particular pharmaceutical value (the former) or act as carriers making the drug easier to dissolve, ingest and process (the latter). The primary pharmaceutical value of Cialis Black is also hidden in its main ingredient which is Tadalafil. Tadalafil is an enzyme type which have been discovered and patented by the ICOS biotech company less than a decade ago. The active ingredient was later developed and advertised by a joint venture of ICOS Corporation and Eli Lilly Company under the brand name Cialis. Being the third patented impotence treatment pill in the world (after Sildenafil Citrate and Vardenafil), Cialis has become very popular ever since its FDA approval and introduction to the pharmaceutical market of the United States and Europe.

A Bit of Chemistry
In order to understand the principle of Tadalafil action it is important to envision the processes which take part in a male’s body when he is sexually aroused. Erection is a complex action of nervous system signals and various chemicals interaction. One of the crucial chemicals in attaining and maintaining penile erection is Cyclic GMP. CGMP is one of the messengers which is released into the bloodstream causing blood vessels dilatation when the sexual stimulation takes place. By increasing the blood flow cGMP makes the male’s sex organ harden and erect. The cGMP’s antipode is a phosphodiesterase type 5 (PDE5 in short), it breaks down the cyclic GMP and thereby softens the penile tissues. That is where Tadalafil comes into play: Black Cialis active ingredient is a PDE5 inhibitor which means that it stops and postpones the cGMP breakdown allowing for sustained erection.

In fact, Tadalafil is a very wise chemical, since it works only in case of sexual stimulation from outside. Its principle of work is based on natural processes of the male’s body, thereby it will not cause occasional erection making you feel embarrassed.

Tadalafil Treatment Approaches
There exist two ways to treat erectile dysfunction with Tadalafil: to take the pill on 'as needed' basis or at low daily dose. The first approach implies oral administration of a Cialis Black pill 20-60 mins prior to sexual activity. In this case the drug will start working within an hour and remain effective for about 36 hours (it is often called a 'weekend pill' for its long-lasting effect). In case you take Cialis only when sexual intercourse is anticipated, there is no need to take more than one pill per day. In case of 'as needed' intake the prescribed dose is 10 to 20mg (it is appointed by the health care professional in correspondence to various factors like response, tolerance, age etc.). The dose can be both lowered and increased if needed.

However, Tadalafil can be also taken as a daily dose. This version is more beneficial for those who expect regular sexual intercourse (there will be no need for the anticipatory dose). The pills taken on a daily basis feature much lower dose (2.5 or 5mg).